There are 60 calories in a 1 slice serving of Kraft American Cheese Slice. Get full nutrition facts for other Kraft products and all your other favorite brands. Add Kraft Singles unmistakable creamy melt and American flavor to your cheeseburgers, grilled cheese sandwiches, and so many meals!. Get great flavor with Kraft® Singles American cheese slices (24ct pack). These singles melt perfectly on cheeseburgers and grilled cheese sandwiches.