Calories in Homemade Macaroni And Cheese based on the calories, fat, protein, carbs and other nutrition information submitted for Homemade Macaroni And. Find detailed calories information for Macaroni and Cheese including Popular Types of Macaroni & Cheese and Other Types of Macaroni & Cheese. View the nutrition for Large Macaroni & Cheese, including calories, carbs, fat, protein, cholesterol, and more (Popeyes). Want to use it in a meal plan? Head to .